NeuroMab™ Anti-VGlut1 BBB Shuttle Antibody, Clone N28/9
[CAT#: NRZP-0423-ZP463]
- Species Reactivity:
- Rat; Mouse; Human
- Applications:
- WB; IHC; ICC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-VGlut1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1 (also known as Vesicular glutamate transporter 1, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Bnpi, Solute carrier family 17 member 7 and Slc17a7, accession number Q62634)
Mouse: 97% identity (66/68 amino acids identical)
Human: 95% identity (65/68 amino acids identical)
<50% identity with VGlut2 or VGlut3
Mouse: 97% identity (66/68 amino acids identical)
Human: 95% identity (65/68 amino acids identical)
<50% identity with VGlut2 or VGlut3
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N28/9
Applications
WB; IHC; ICC
Application Notes
Does not react with VGlut2 or VGlut3
Research Areas
Transporters
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
VGlut1
Official Name
SLC17A7
Full Name
VGlut1
Alternative Names
SLC17A7; BNPI; VGLUT1; solute carrier family 17 member 7
Uniprot ID
Q62634
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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