NeuroMab™ Mouse Anti-CD68 Monoclonal Antibody (CBP1588)

Product Overview

Description

Mouse anti-human CD68 antibody recognizes human CD68 cell surface antigen, a ~110 kDa glycoprotein mainly expressed by macrophages and monocytes.

Immunogen

Phytohaemagglutinin stimulated peripheral blood mononuclear cells.

Species Reactivity

Human; Primate; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP1588

Applications

Relevant Diseases

Alzheimer's Disease

Research Areas

Growth and Development

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1373

Product Properties

Form

Liquid

Formulation

PBS
0.09% Sodium Azide
1% BSA

Concentration

0.05 mg/ml

Purification

Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend micr°Centrifugation before use.

Target

CD68

Official Name

CD68

Full Name

CD68 Molecule

Alternative Names

CD68 Molecule; CD68 Antigen; Scavenger Receptor Class D, Member 1; Macrophage Antigen CD68; GP110; Macrosialin; SCARD1; LAMP4

Gene ID

968(Human); 12514(Mouse); 287435(Rat)

Uniprot ID

P34810(Human); P31996(Mouse)

References

1. Davey, F.R. et al. (1988) Monoclonal antibody (Y1/82A) with specificity towards peripheral blood monocytes and tissue macrophages.
2. Micklem, K. et al. (1989) A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies.
3. Pulford, K.A. et al. (1990) Distribution of the CD68 macrophage/myeloid associated antigen.
4. Holness, C.L. & Simmons, D.L. (1993) Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins.
5. Mahida, Y.R. et al. (1997) Migration of human intestinal lamina propria lymphocytes, macrophages and eosinophils following the loss of surface epithelial cells.

Publications