Immortalized Human Cerebral Microvascular Endothelial Cells

Excellent

This cell line is a great resource for BBB studies

The CMEC/D3 cell line has been a reliable model for studying the BBB in vitro. We used it to investigate drug permeability, and the results were consistent with in vivo data. The cells were easy to culture and maintained their characteristic morphology throughout the experiments. Highly recommend it for BBB-related studies.

Excellent

Ease of culturing and reproducibility of the results

These cells offer a robust and reproducible model for the human blood-brain barrier. We utilized the CMEC/D3 cell line for co-culture experiments with astrocytes, and the barrier properties were well-maintained. The tight junction integrity was particularly impressive, as confirmed by TEER measurements.

Excellent

The cells are robust and easy to work with

The CMEC/D3 cells are an excellent tool for modeling the BBB in drug delivery studies. They form a strong, consistent barrier that mimics the in vivo environment well. My team has been using them to test nanoparticle delivery systems, and the data we've gathered has been invaluable.

Excellent

These cells are an essential tool for our lab

Our lab has been using the CMEC/D3 cell line to study neuroinflammation, and it has performed exceptionally well. The cells responded to cytokine treatments as expected, making it a reliable model for understanding BBB dynamics under inflammatory conditions.

Excellent

We've observed excellent barrier properties

The CMEC/D3 cells provided us with a high-quality in vitro model for BBB research. We used them to study the effects of hypoxia on endothelial permeability and found the results to be highly reproducible. The cells are easy to handle, and their growth characteristics are very stable.