NeuroMab™ Mouse Anti-Rat CD45 Monoclonal Antibody (CBP2390)
[CAT#: NAB2010414LS]
Anti-CD45 Monoclonal Antibody [Biotin]
- Host Species:
- Mouse
- Species Reactivity:
- Rat
- Applications:
- FC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
CD45 is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets. CD45RA is one of the CD45 isoforms with a molecular weight of 200-220 kD. It is expressed almost exclusively on B cells. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins, including galectin-1, CD2, CD3, and CD4.
Immunogen
Leukocyte common antigen purified from rat splenocytes.
Species Reactivity
Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP2390
Applications
FC
Application Notes
FCM (≤0.25 µg per 106 cells in 100 µl volume); IHC (2.5-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1759
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Handling Advice
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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