NeuroMab™ Anti-Neuroligin-1 BBB Shuttle Antibody, Clone N97A/31
[CAT#: NRZP-0423-ZP294]
- Species Reactivity:
- Rat; Mouse
- Applications:
- WB; IHC; ICC
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-Neuroligin 1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 718-843 (cytoplasmic C-terminus) of rat Neuroligin-1 (also known as Nlgn1 and Kiaa1070, accession number Q62765)
Mouse: 99% identity (125/126 amino acids identical)
Human: 99% identity (125/126 amino acids identical)
>40% identity with Neuroligin-2 and -3
Mouse: 99% identity (125/126 amino acids identical)
Human: 99% identity (125/126 amino acids identical)
>40% identity with Neuroligin-2 and -3
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N97A/31
Applications
WB; IHC; ICC
Application Notes
Does not cross-react with other Neuroligins
Research Areas
CAMs
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
Neuroligin 1
Official Name
NLGN1
Full Name
Neuroligin-1
Alternative Names
NLGN1; NL1; neuroligin 1
Uniprot ID
Q62765
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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