NeuroMab™ Anti-SAPAP1/2 BBB Shuttle Antibody, Clone N238/31
[CAT#: NRZP-0423-ZP379]
- Species Reactivity:
- Rat; Mouse; Human
- Applications:
- WB; IHC; ICC
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-SAPAP1/2 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 772-992 (C-terminus) of rat SAPAP1 (also known as disks largeassociated protein 1, DAP-1, guanylate kinase-associated protein, GKAP, SAP90/PSD-95- associated/binding protein 1 and Dlgap1, accession number P97836)
Mouse: 99% identity (200/201 amino acids identical)
Human: 99% identity (199/201 amino acids identical)
>50% identity with SAPAP2 and other SAPAPs
Mouse: 99% identity (200/201 amino acids identical)
Human: 99% identity (199/201 amino acids identical)
>50% identity with SAPAP2 and other SAPAPs
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N238/31
Applications
WB; IHC; ICC
Application Notes
Cross-reacts with SAPAP2;Does not cross-react with SAPAP3 or SAPAP4
Research Areas
Scaffolds
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
SAPAP1/2
Official Name
SAPAP1/2
Full Name
SAPAP1/2
Alternative Names
SAPAP1; SAPAP2
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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