NeuroMab™ Mouse Anti-NEFL Monoclonal Antibody (CBP1604)
[CAT#: NAB2007FY131]
Mouse Monoclonal [3G2] to NEFL
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- WB
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Mouse anti-human neurofilament antibody can recognize neurofilament, also known as light molecular weight neurofilament protein, neurofilament light polypeptide, neurofilament protein, light chain, neurofilament subunit NF-L, neurofilament triad L protein, neurofilament, Light polypeptide 68kDa and protein phosphatase 1 regulatory subunit 110. Neurofilament is a type IV intermediate filament heteropolymer composed of light chain, medium chain and heavy chain. Neurofilaments include an axoskeleton and functionally maintain the caliber of neurons. They may also play a role in intracellular transport to axons and dendrites. The NEFL gene encodes light chain neurofilament protein. Mutations in NEFL can cause Charcot-Marie-Tooth disease type 1F (CMT1F) and type 2E (CMT2E), which are diseases of the peripheral nervous system characterized by obvious neuropathy.
Immunogen
Recombinant protein fragment corresponding to amino acids 1-360 of human neurofilament (NP_006149) produced in E. coli.
Species Reactivity
Human; Mouse
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP1604
Applications
WB
Application Notes
WB (1/1000)
Research Areas
Growth and Development
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1379
Product Properties
Form
Liquid
Formulation
PBS
0.09% Sodium Azide
1% BSA
50% Glycerol
0.09% Sodium Azide
1% BSA
50% Glycerol
Purification
Mouse monoclonal antibody purified by affinity chromatography from ascites.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Target
Target
Neurofilament L
Official Name
NEFL
Full Name
Neurofilament light polypeptide
Alternative Names
NEFL; CMT1F; CMT2E; NF-L; NF68; NFL; PPP1R110; neurofilament; light polypeptide; neurofilament light; CMTDIG
Publications
Publications (0)
Neural Genes
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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