Mouse Anti-DJ1 Monoclonal Antibody (CBP6719)
[CAT#: NAB2007FY1580]
Mouse Monoclonal to DJ1
- Host Species:
- Mouse
- Species Reactivity:
- Human; Cow; no reactivity with rat or mouse
- Applications:
- WB; IF; IHC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
DJ1, also known as PARK7, is a cytoplasmic protein that belongs to the DJ1/ThiJ/PfpI protein superfamily and has multiple functions in eukaryotes and bacteria (1). DJ1 was originally cloned as an oncogene, which was co-transformed with mutated H-ras (2). Then a mutation associated with a rare form of autosomal recessive early-onset Parkinson's disease was found in the DJ1 gene, which led to DJ1 also known as PARK7 (3). One or more functions of DJ1 are not yet clear, and may include redox-sensitive chaperone proteins, oxidative stress sensors, and it can protect neurons from oxidative stress and cell death (4-6). Enhancing DJ1 activity may be a new method for the treatment of chronic neurodegenerative diseases (such as Parkinson's disease) and acute injuries (such as stroke) (7).
Immunogen
Full-length recombinant human DJ1 expressed and purified in E. coli.
Species Reactivity
Human; Cow; no reactivity with rat or mouse
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP6719
Applications
WB; IF; IHC
Application Notes
WB: 1:5000
IF/IHC: 1:1000
IF/IHC: 1:1000
Product Properties
Form
Liquid
Formulation
50% PBS, 50% glycerol
Preservatives
5mM NaN3
Concentration
1 mg/ml
Shipping
Gel Pack
Storage
Store at 4°C for short term, for longer term at -20°C
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
Publications
Publications (0)
Neural Antibodies
Neural Genes
Neural Cell Lines
Kits
For Research Use Only. Not For Clinical Use.
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