NeuroMab™ Anti-Ataxin-1 wild-type, Clone N65/37 (CBP8135)

Product Overview

Immunogen

Synthetic peptide amino acids 746-761 (RKRRRWSAPETRKLEK) of mouse ataxin-1 (also known as spinocerebellar ataxia type 1 protein homolog, accession number P54254)
Rat: 93% identity (15/16 amino acids identical)
Human: 87% identity (14/16 amino acids identical)

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8135

Applications

WB; IHC; ICC

Application Notes

No cross-reactivity against phosphoS751-Ataxin-1;Minimal cross-reactivity against S751A mutant of Ataxin-1 by ELISA and immunofluorescence and negative by immunoblot (right)

Research Areas

Rare Disease

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

Ataxin 1

Official Name

ATXN1

Full Name

Ataxin-1, WT

Alternative Names

ATXN1; ATX1; D6S504E; SCA1; ataxin 1

Uniprot ID

P54254

Product Pictures

Fig. 1 Transfected cell immunoblot: extracts of COS-1 cells transfected with Ataxin1-WT, Ataxin-1-S751A or Kv2.1 plasmid and probed with N65/37 TC supe.