NeuroMab™ Anti-Clcn3, Clone N258/5 (CBP8177)

[CAT#: NRP-0422-P76]

Species Reactivity:: Human; Mouse; Rat

Applications:: WB; IHC; ICC

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Product Overview

Immunogen

Synthetic peptide amino acids 98-115 (CKDRERHRRINSKKKESA, cytoplasmic N-terminus) of human Clcn3 (also known as H(+)/Cl(-) exchange transporter 3, Chloride transporter ClC-3, Chloride channel protein 3 and Clc3, accession number P51790)
Mouse: 100% identity (18/18 amino acids identical)
Rat: 100% identity (18/18 amino acids identical)
<70% identity with Clcn4 and Clcn5

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8177

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with Clcn4 or Clcn5 (based on KO validation results)

Research Areas

Ion channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

CLC3

Official Name

CLCN3

Full Name

Clcn3

Alternative Names

CLCN3; CLC3; ClC-3; chloride voltage-gated channel 3

Uniprot ID

P51790

Product Pictures

Fig. 1 Immunoblot versus crude membranes from adult rat brain (RBM) and WT and Clcn3 KO mouse brains probed with N258/5 (left) and N52A/42 (right) TC supe.