NeuroMab™ Anti-HCN2 cyclic nucleotide-gated channel, Clone N71/37 (CBP8262)

Product Overview

Immunogen

Fusion protein amino acids 761-863 (cytoplasmic C-terminus) of rat HCN2 (also known as potassium /sodium hyperpolarization-activated cyclic nucleotide gated channel 2, accession number Q9JKA9)
Mouse: 98% identity (101/103 amino acids identical)
Human: 82% identity (86/104 amino acids identical)
<50% identity with HCN1, HCN3 and HCN4

Species Reactivity

Mouse; Rat

Clonality

Monoclonal

Clone Number

CBP8262

Applications

WB; IHC; IP; ICC

Application Notes

No cross-reactivity against HCN1

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

HCN2

Official Name

HCN2

Alternative Names

Hyperpolarization Activated Cyclic Nucleotide Gated Potassium And Sodium Channel 2; Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 2; Brain Cyclic Nucleotide-Gated Channel 2; BCNG-2; BCNG2; Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2; Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2; HAC-1;

Product Pictures

Fig. 1 Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and of COS-1 cells transfected with GFPHCN1, GFP-HCN2 or Kv2.1 plasmids and probed with N71/37 (left), K89/34 (middle) or a control (right) TC supe.

Fig. 2 Immunoblots on brain membranes prepared from whole rat (RBM) and mouse (MBM) brain, and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].