NeuroMab™ Anti-Nav1.8 sodium channel, Clone N134/12 (CBP8385)

[CAT#: NRP-0422-P284]

Species Reactivity:: Human; Mouse; Rat

Applications:: WB; IHC; ICC

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Product Overview

Immunogen

Fusion protein amino acids 1724-1956 (cytoplasmic C-terminus) of rat Nav1.8 (also known as Sodium channel protein type 10 or X subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.8, Peripheral nerve sodium channel 3, PN3 or Sensory neuron sodium channel, accession number Q62968)
Mouse: 93% identity (220/235 amino acids identical)
Human: 85% identity (200/234 amino acids identical)
>50% identity with Nav1.7 and Nav1.5

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

CBP8385

Applications

WB; IHC; ICC

Application Notes

Does not react with Nav1.7

Research Areas

Na+ channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

SCN10A

Official Name

SCN10A

Full Name

Nav1.8 Na+ channel

Alternative Names

hPN3; Nav1.8; PN3; SCN10A; SNS

Uniprot ID

Q62968

Product Pictures

Fig. 1 Stable/transfected cell immunoblot: extracts of HEK cells stably expressing Nav1.7 and COS cells transiently transfected with GFP-tagged Nav1.8 or untagged Kv2.1 plasmids and probed with N134/12 TC supe.