NeuroMab™ Anti-CALB1/calbindin BBB Shuttle Antibody, Clone L109/57
[CAT#: NRZP-0423-ZP54]
- Species Reactivity:
- Human; Rat; Mouse
- Applications:
- WB; IHC; ICC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-Calbindin BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-261 (full-length) of human CALB1 (also known as Calbindin D28, Vitamin D-dependent calcium-binding protein, D-28K, Spot 35 protein, CAB27 and PCD-29, accession number P05937)
Rat: 98% identity (257/261 amino acids identical)
Mouse: 98% identity (257/261 amino acids identical)
<60% identity with CALB2/Calretinin
Rat: 98% identity (257/261 amino acids identical)
Mouse: 98% identity (257/261 amino acids identical)
<60% identity with CALB2/Calretinin
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
L109/57
Applications
WB; IHC; ICC
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
Calbindin
Official Name
CALB1
Full Name
Calbindin
Alternative Names
CALB
Uniprot ID
P05937
Publications
Publications (0)
Neural Antibodies
Kits
For Research Use Only. Not For Clinical Use.
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