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Creative Biolabs

NeuroMab™ Anti-CD32b Antibody(NRP-0422-P1796)

[CAT#: NRP-0422-P1796]

Functional antibody against Human CD32b

Host Species:
Human
Species Reactivity:
Human
Applications:
ELISA; WB; ADCC; Cyt; Block; In Vitro; In Vivo

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Product Overview

Description

The isolated monoclonal antibody binds to human CD32b, which is essential for novel treatments based on therapeutic antibodies, including monoclonal antibody treatment of B-cell lymphoproliferative disorders. Such identification and generation has been hindered by the homology of CD32A to CD32b within the extracellular region. The monoclonal anti-CD32b antibody can be used as an adjuvants, i.e. by boosting an immune response through blocking of the inhibitory effects of CD32b.

Immunogen

Recombinant soluble extracellular domain

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Applications

ELISA; WB; ADCC; Cyt; Block; In Vitro; In Vivo

Relevant Diseases

Systemic Lupus Erythematosus; Malaria
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

CD32b

Official Name

FCGR2B

Full Name

Fc fragment of IgG receptor IIb

Alternative Names

FCGR2B; CD32; CD32B; FCG2; FCGR2; IGFR2; Fc fragment of IgG receptor IIb; FcRII-c; FCGR2C

Gene ID

Uniprot ID

Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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