NeuroMab™ Anti-KChIP3 potassium channel BBB Shuttle Antibody, Clone K66/38
[CAT#: NRZP-0423-ZP186]
- Species Reactivity:
- Rat; Mouse; Human
- Applications:
- WB; IHC; IP; ICC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-KCNIP3 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-256 (full-length) of rat KChIP3 (also known as Kv channel-interacting protein 3, Kcnip3, A-type potassium channel modulatory protein 3, Calsenilin, Csen, DREantagonist modulator and Dream, accession number Q9JM47)
Mouse: 98% identity (251/256 amino acids identical)
Human: 93% identity (239/256 amino acids identical)
>50% identity with KChIP1, KChIP2 and KChIP4
Mouse: 98% identity (251/256 amino acids identical)
Human: 93% identity (239/256 amino acids identical)
>50% identity with KChIP1, KChIP2 and KChIP4
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
K66/38
Applications
WB; IHC; IP; ICC
Application Notes
Does not cross-react with KChIP1, KChIP2 or KChIP4
Research Areas
K+ channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
KCNIP3
Official Name
KCNIP3
Full Name
KChIP3 K+ channel
Alternative Names
KCNIP3; CSEN; DREAM; KCHIP3; potassium voltage-gated channel interacting protein 3
Uniprot ID
Q9JM47
Publications
Publications (0)
Neural Antibodies
Neural Genes
For Research Use Only. Not For Clinical Use.
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