NeuroMab™ Anti-Tau; pTau BBB Shuttle Antibody(NRZP-1022-ZP3103)
[CAT#: NRZP-1022-ZP3103]
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- WB; IHC; ICC; In Vitro; In Vivo
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human; Mouse
Clonality
Monoclonal
Host Species
Mouse
Applications
WB; IHC; ICC; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
TaupTau
Official Name
MAPT
Product Pictures
WB
Figure 1 shows the characterization of the specificity of the tau antibody by immunoblot analysis of total brain lysates from nTg, tau KO, and PS19 tau Tg mice using actin as a control.
WB
Figure 2 shows the specificity of tai antibodies raised against the tau peptide p193-211, as determined by immunoblotting with recombinant tau protein phosphorylated in vitro by p42 MAPK or GSK3β.
WB
Figure 3 shows the biochemical characterization of sarcosyl-insoluble tau detected by a tau antibody in human brain lysates from AD patients.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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