Mouse Anti-GAP43 Monoclonal Antibody (CBP6663)

Product Overview

Description

GAP43 is a kind of abundant protein, concentrated in a large number of developing neurons, especially at the growth tip, that is, the growth cone. One group found it because it became unregulated during toad optic nerve regeneration and named it "growth-associated protein 43". 43 refers to the apparent molecular weight on the SDS-PAGE gel (1). GAP43 is very charged and will not run on SDS-PAGE in a way that accurately reflects its molecular weight, because human GAP43 has 238 amino acids and the actual molecular weight is 24.8kDa. The same GAP43 formulation will also produce different SDS-PAGE molecular weights, depending on the percentage of acrylamide content in the gel. The protein appears relatively large on a gel with a higher acrylamide concentration.

Immunogen

Recombinant full-length human GAP43 expressed and purified in E. coli

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6663

Applications

WB; IF; IHC

Application Notes

WB: 1:1,000-5,000 IF/ICC and IHC: 1:1,000-5,000

Product Properties

Form

Liquid

Formulation

50% PBS, 50% glycerol

Preservatives

5mM NaN3

Concentration

1 mg/ml

Shipping

Gel Pack

Storage

Stable at 4°C for one year, for longer term store at -20°C

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only

Target

GAP43

Official Name

GAP43

Full Name

Growth Associated Protein 43

Alternative Names

Growth Associated Protein 43; Axonal Membrane Protein GAP-43; Neural Phosphoprotein B-50; Neuron Growth-Associated Protein 43; Nerve Growth-Related Peptide GAP43; Calmodulin-Binding Protein P-57;