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Creative Biolabs
Product

Mouse Anti-aldolase a, B and C Monoclonal Antibody (CBP6728)

[CAT#: NAB2007FY1589]

Mouse Monoclonal to aldolase a, B and C

Host Species:
Mouse
Species Reactivity:
Human; Rat; Mouse
Applications:
WB; IF; IHC

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Product Overview

Description

Aldolase is an important glycolytic cytoplasmic enzyme that can catalyze the reversible conversion of fructose 1,6-diphosphate to glyceraldehyde 3-phosphate. There are three aldolase isoenzymes coded by three different genes in mammals, namely aldolase A, B and C. Aldolase A is abundantly expressed in muscle enzymes, and aldolase B is expressed abundantly in the liver, which is regarded as a liver-specific enzyme (1-5). In adults, aldolase C is a brain-specific isoenzyme expressed in astrocytes and several types of neurons, especially Purkinje cells (4). Therefore, appropriate aldolase C antibodies can be used to identify astrocytes in cell cultures and slice materials, and the enzyme may be overexpressed in some forms of cancer (6).

Immunogen

Recombinant human full-length aldolase C

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6728

Applications

WB; IF; IHC

Application Notes

WB: 1:10000
IF/ICC or IHC: 1:1000-1:5000
Product Properties

Form

Liquid

Formulation

50% PBS, 50% glycerol

Preservatives

5mM NaN3

Concentration

1 mg/ml

Shipping

Gel Pack

Storage

Store at 4°C for short term, for longer term at -20°C

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

Aldolase C

Official Name

ALDOC

Full Name

Aldolase C, fructose-bisphosphate

Alternative Names

ALDOC; ALDC; Aldolase C; aldolase; fructose-bisphosphate C

Gene ID

230 (Human); 11676 (Mouse); 24191 (Rat)

Uniprot ID

P09972 (Human); P05063 (Mouse);
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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