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Creative Biolabs

Mouse Anti-Aldolase C: N-terminus specific Monoclonal Antibody (CBP6627)

[CAT#: NAB2007FY1488]

Mouse Monoclonal to Aldolase C: N-terminus specific

Host Species:
Mouse
Species Reactivity:
Human; Rat; Mouse; Cow; Porcine
Applications:
WB; IF; IHC

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Product Overview

Description

Aldolase is an important glycolytic cytoplasmic enzyme that can catalyze the reversible conversion of fructose 1,6-diphosphate to glyceraldehyde 3-phosphate. There are three aldolase isoenzymes coded by three different genes in mammals, namely aldolase A, B and C. Aldolase A is abundantly expressed in muscle enzymes, and aldolase B is expressed abundantly in liver-specific enzymes (1-5). In adults, aldolase C is a brain-specific isoenzyme expressed in astrocytes and several types of neurons, especially Purkinje cells (4). Therefore, the appropriate aldolase C antibody can be used to recognize astrocytes in cell cultures and sections, and the enzyme may be overexpressed in some forms of cancer (6). Recent studies have also shown that the detection of aldolase C in the blood may be a useful indicator for judging the severity of traumatic brain injury (7).

Immunogen

N-terminal sequence MPHSYPALSAEQKKELSDIA

Species Reactivity

Human; Rat; Mouse; Cow; Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6627

Applications

WB; IF; IHC

Application Notes

WB: 1:2000
IF/ICC or IHC: 1:1000
Product Properties

Form

Liquid

Formulation

50% PBS, 50% glycerol

Preservatives

5mM NaN3

Concentration

1 mg/ml

Shipping

Gel Pack

Storage

Store at 4°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

Aldolase C

Official Name

ALDOC

Full Name

Aldolase C, fructose-bisphosphate

Alternative Names

ALDOC; ALDC; Aldolase C; aldolase; fructose-bisphosphate C

Gene ID

230 (Human); 11676 (Mouse); 24191 (Rat)

Uniprot ID

P09972 (Human); P05063 (Mouse);
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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