Mouse Anti-NEFH Monoclonal Antibody (CBP6776)

Product Overview

Description

Neuroinflammation broadly defines the collective response Immune response in the brain and spinal cord Injuries and illnesses. Central nervous system inflammation (CNS) Usually related to different levels of organization Damage, such as loss of myelin sheath and neurons. Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Epitope

Binds to an located within the peptide sequence ECRIGFGPIPFSLPE

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6776

Applications

IHC; WB

Application Notes

IHC: 1:500-1:1000
WB: 1 µg/ml

Research Areas

Neuron

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, 40% glycerol

Preservatives

0.02% Sodium azide

Concentration

1 mg/ml

Purification

Protein A purified

Shipping

Gel Pack

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only

Target

NEFH

Official Name

NEFH

Full Name

Hypophosphorylated Neurofilament H

Alternative Names

Neurofilament Heavy; Neurofilament Heavy Polypeptide; Neurofilament; Heavy Polypeptide 200kDa; Neurofilament Triplet H Protein; 200 KDa Neurofilament Protein; NF-H; NFH; KIAA085; CMT2CC

Publications