NeuroMab™ Anti-Slc18a2/VMAT2, Clone N449/73 (CBP8569)

Product Overview

Immunogen

Fusion protein amino acids 42-132 (first lumenal domain) of mouse Slc18a2 (also known as Synaptic vesicular amine transporter, Monoamine transporter, Solute carrier family 18 member 2, Vesicular amine transporter 2, VAT2, Svmt, Svat and Vmat2, accession number Q66L40)
Rat: 82% identity (75/92 amino acids identical)
Human: 73% identity (67/92 amino acids identical)
<30% identity with Slc18a1/VMAT1

Species Reactivity

Rat; Mouse; Human

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

CBP8569

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with Slc18a1/VMAT1 or Slc18a3/VAChT

Research Areas

Transporters

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

VMAT2

Official Name

SLC18A2

Full Name

VMAT2

Alternative Names

SLC18A2; SVAT; SVMT; VAT2; VMAT2; solute carrier family 18 member A2; Vesicular monoamine transporter 2; PKDYS2

Uniprot ID

Q66L40

Product Pictures

Fig. 1 Immunoblot against extracts of COS cells transiently transfected with Myc/Flag-tagged VMAT1, VMAT2, VAChT or Kv2.1 plasmid probed with N449/73 (left) or rabbit anti-Flag (right).

Fig. 2 immunoblot on crude membrane fractions from whole mouse (MBM) and rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] and cerebellum [HBM(Cb)] probed with N449/73 (left) and N52A/42 (right) TC supe.