AAV2/9-CMV_bGI-EGFP-2A-TetTox-pA [Synaptic Inhibition]

[CAT#: NTA-2012-ZP266]

Tracer Type:: Neuronal Synaptic Depression

Applications:: Synaptic Inhibition

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Product Overview

Description

The CMV-bGI promoter is a combination of the CMV promoter, the human herpes virus intron region and the human β-globin intron region. Like CAG, it is a constitutive promoter with a strong promoter without cell tissue specificity.

TetTox, also known as TeNT, is the light chain of Tetanus toxin. It is a protease that can specifically degrade VAMP2, inhibit the release of synaptic glutamate transmitter vesicles, and interrupt the transmission of nerve electrical signals.