AAV2/9-hSyn-EGFP-2A-TetTox-WPRE-pA [Synaptic Inhibition]

[CAT#: NTA-2012-ZP265]

Tracer Type:: Neuronal Synaptic Depression

Applications:: Synaptic Inhibition

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Product Overview

Description

The hSyn promoter, also called hSyn1 promoter, is cloned from the promoter region of human synapsin1 (Synapsin1), is about 0.5kb in length, and expresses specifically in neurons.

TetTox, also known as TeNT, is the light chain of Tetanus toxin. It is a protease that can specifically degrade VAMP2, inhibit the release of synaptic glutamate transmitter vesicles, and interrupt the transmission of nerve electrical signals.