AAV2/9-mCaMKIIa-mCherry-P2A-TetTox-WPRE-pA [Synaptic Inhibition]
[CAT#: NTA-2012-ZP271]
- Tracer Type:
- Neuronal Synaptic Depression
- Applications:
- Synaptic Inhibition
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SPECIFIC INQUIRY
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Description
TetTox, also known as TeNT, is the light chain of Tetanus toxin. It is a protease that can specifically degrade VAMP2, inhibit the release of synaptic glutamate transmitter vesicles, and interrupt the transmission of nerve electrical signals.
The mCaMKIIa promoter, cloned from the promoter region of mouse calmodulin-dependent protein kinase IIa, is 1.3 kb in length, and is specifically expressed in excitatory neuronal cells.
The mCaMKIIa promoter, cloned from the promoter region of mouse calmodulin-dependent protein kinase IIa, is 1.3 kb in length, and is specifically expressed in excitatory neuronal cells.
Tracer Type
Neuronal Synaptic Depression
Serotype
AAV9
Virus Type
Adeno-Associated Virus (AAV)
Applications
Synaptic Inhibition
Research Areas
Neural Circuit Mapping
Promoter
CaMKIIa
Expression
Tet-on
Properites
Fluorophore
mCherry
Data
Publications
Publications (0)
Neural Tracers
For Research Use Only. Not For Clinical Use.
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