NeuroMab™ Anti-CD3 BBB Shuttle Antibody, Clone NR287P
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- FC; In Vitro; In Vivo
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 Flow cytometric analysis of PG3055 and PG3056 binding to CD3 on purified human T cells after incubation of PG3055 and PG3056 in IMDM+10% FBS medium for 7 days at 2-8°C or 37°C.
Figure 2 Flow cytometry analysis of the binding of variants PG3872, PG3873 and PG3905 to CD3 on HPB-ALL cells with PG3056 as a baseline control
Figure 3 Flow cytometry analysis of CD3 on HPB-ALL cells binding variants PG3874, PG3878, PG3883, PG3886 and PG3891, including PG3056 as a baseline control.
Figure 4 Flow cytometry analysis of PG5192-5197 variant HPB-ALL cells binding to CD3, PG3056 as a baseline control
Figure 5 Binding of 5196×4327 DM-Fc bsAb to membrane-expressed CD3 (HPB-ALL) and CLEC12A (HL-60)
Figure 6 5196×4327 DM-Fc bsAb retained CLEC12A-specific activation of CD4 and CD8 T cells, as reflected by upregulation of the early activation marker CD69.
Figure 7 5196×4327 induces antigen-mediated lysis of target cells
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