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Creative Biolabs

NeuroMab™ Mouse Anti-CD3 Monoclonal Antibody (CBP2679)

[CAT#: NAB20101754CR]

Mouse Monoclonal (UCHT1) to CD3

Host Species:
Mouse
Species Reactivity:
Human
Applications:
FC; ELISA

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Product Overview

Description

CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction.

Expression Host

Mammalian cells

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2679

Applications

FC; ELISA

Research Areas

GPCR

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1889
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

500 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD3

Official Name

CD3

Full Name

CD3e molecule, epsilon (CD3-TCR complex)

Alternative Names

CD3E; T3E; TCRE

Gene ID

919(Human); 12503(Mouse); 25300(Rat)

Uniprot ID

P20963(Human); P04235(Mouse); P19377(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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