NeuroMab™ Anti-pTau Antibody(NRP-0422-P1682)

Product Overview

Description

The monoclonal antibody can be used for the detection of phosphorylated aggregated tau and for the diagnosis of diseases involving phosphorylated aggregated tau.

Immunogen

Yeast-purified tau

Epitope

scFv

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

ELISA; WB; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

pTau

Official Name

pTau

Full Name

phosphorylated tau

Alternative Names

MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40

Product Pictures

Figure 1: Analysis of novel mAbs on transgenic mouse and human brain samples.

Western blot analysis of brain extracts from control mice (FVB), knock-out mice and transgenic (Tg) mice expressing a clinical mutant of human tau (Tau-P301L). The age of the mice is indicated between brackets. The arrow on the second blot indicates high molecular weight tau complexes. The antibodies used are ADx215 (YT1.15), ADx210 (YT1.10) and the commercial phosphorylation-specific antibody AT100 (exposure time of 30 min for ADx210 (YT1.10) and AT100, and 30 sec for ADx215 (YT1.15)).

Publications