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Creative Biolabs

NeuroMab™ Mouse Anti-Human CD25 Monoclonal Antibody (CBP2337)

[CAT#: NAB2010321LS]

Anti-CD25 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
FC

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Product Overview

Description

CD25 is a 55 kD type I transmembrane glycoprotein also known as low affinity IL-2 receptor α chain or Tac. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses. CD25 associates with IL-2 receptor β (CD122) and common γ (CD132) chains to form a high affinity IL-2R complex.

Immunogen

Human PHA-induced lymphocyte cells

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2337

Applications

FC

Application Notes

FCM (≤0.5 µg per million cells in 100 µl volumel)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1725
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD25

Official Name

IL2RA

Full Name

Interleukin-2 receptor alpha chain

Alternative Names

IL2RA; CD25; IDDM10; IL2R; TCGFR; p55; IMD41; interleukin 2 receptor subunit alpha

Gene ID

3559 (Human); 16184 (Mouse)

Uniprot ID

P01589 (Human); P15090 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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