NeuroMab™ Anti-CD25 BBB Shuttle Antibody(NRZP-1222-ZP1157)
[CAT#: NRZP-1222-ZP1157]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- In Vitro
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SPECIFIC INQUIRY
inquiryProduct Overview
Description
The anti-CD25 antibody is optimized to deplete Tregs whilst preserving IL-2-STAT5 signaling on effector T cells, and demonstrate synergy with immune checkpoint blockade in vivo. The anti-human CD25 antibody with equivalent features demonstrates, in both non-human primates and humanized mouse models, efficient Treg depletion with no overt immune-related toxicities.
Species Reactivity
Human
Host Species
Mouse
Applications
In Vitro
Relevant Diseases
Neuroinflammation
Target
Target
CD25
Official Name
Il2RA
Full Name
interleukin 2 receptor, alpha chain
Alternative Names
IL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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