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Creative Biolabs

Mouse Anti-TRPM4 Monoclonal Antibody (CBP6846)

[CAT#: NAB2007FY1795]

Alzheimer's disease (AD), amyotrophic lateral
sclerosis (ALS), Lewy body dementia (LBD),

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC; WB; IF

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Product Overview

Description

Neuroinflammatory process is a key pathogenic factor Brain and spinal cord injury in the back. This applies not only to Acute brain injury and hypoxic-ischemic brain injury Stroke, but also used for chronic infections and neurodegenerative diseases Diseases such as Alzheimer's disease (AD), amyotrophic lateral cord Sclerosis (ALS), Lewy Body Dementia (LBD) and Multiple Sclerosis (Multiple sclerosis). In addition, local inflammation around the tumor also plays a role In the clinical progression and malignancy of glioblastoma, The most aggressive primary brain tumor. The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium. [provided by RefSeq, Mar 2016]

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6846

Applications

IHC; WB; IF

Application Notes

IHC: 1:50-1:200
WB: 1 µg/ml
IF: 2-10 µg/ml

Relevant Diseases

Neuroinflammation; Neurodegenerative Disease; Alzheimer's Disease; Amyotrophic Lateral Sclerosis; Lewy body dementia

Research Areas

Neuroinflammation; Neurodegeneration
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, 40% glycerol

Preservatives

0.02% Sodium azide

Concentration

1 mg/ml

Purification

Protein A purified

Shipping

Gel Pack

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

TRPM4

Official Name

TRPM4

Full Name

Transient Receptor Potential Cation Channel Subfamily M Member 4

Alternative Names

Transient Receptor Potential Cation Channel Subfamily M Member 4; Calcium-Activated Non-Selective Cation Channel 1; Long Transient Receptor Potential Channel 4; Melastatin-4; LTrpC4; HTRPM4

Gene ID

54795(Human)

Uniprot ID

Q8TD43(Human)
Publications

Publications (0)

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