AAV-CAG-DIO-WGA-EGFP-WPREs

[CAT#: NRYF-0324-HZ5]

A fascinating tool to detect neuronal circuitry

Tracer Type:: Neuronal circuitry

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Description

This AAV expresses WGA-EGFP driven by an ubiquitous CAG promoter in Cre recombinase-dependent manner.
When wheat germ agglutinin (WGA) expresses in neurons, it is transported throughout the neuron, secreted, and taken up by synaptically connected neurons. Expression of a WGA and Cre recombinase fusion protein using a viral vector technology in Cre-dependent transgenic animals allows to trace neuronal network connections and to induce topological transgene expression.