NeuroMab™ Anti-GABABR1 GABA-B receptor BBB Shuttle Antibody, Clone N93A/49
[CAT#: NRZP-0423-ZP124]
- Species Reactivity:
- Rat; Mouse; Human
- Applications:
- WB; IHC; ICC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-GABA B Receptor 1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 873-977 (cytoplasmic C-terminus) of rat GABABR1 (also known as Gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1 and Gb1, accession number Q9Z0U4)
Mouse: 98% identity (103/105 amino acids identical)
Human: 97% identity (102/105 amino acids identical)
100% identity between A, B and C isoforms
<30% identity with GABABR2
Mouse: 98% identity (103/105 amino acids identical)
Human: 97% identity (102/105 amino acids identical)
100% identity between A, B and C isoforms
<30% identity with GABABR2
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N93A/49
Applications
WB; IHC; ICC
Application Notes
Does not cross-react with GABABR2
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
GABA B Receptor 1
Official Name
GABBR1
Full Name
GABA(B)R1
Alternative Names
GABBR1; GABABR1; GABBR1-3; GB1; GPRC3A; dJ271M21.1.1; dJ271M21.1.2; gamma-aminobutyric acid type B receptor subunit 1
Uniprot ID
Q9Z0U4
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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