NeuroMab™ Anti-TNFα BBB Shuttle Antibody(NRZP-1022-ZP2705)
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; Cyt; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
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Research Use Only
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Figure 1 shows the effect of anti-TNF monoclonal antibodies 1 and 32 on TNF cytotoxicity in WEHI-164 cells.
Figure 2 shows the potentiation of TNF regressive activity by MAb 32.
Figure 3 shows the enhancement of TNF-induced tumor regression by MAb 32 - dose response at day 1.
Figure 4 shows the binding of radiolabeled TNF to receptors on bovine aortic endothelial cells.
Figure 5 shows the receptor binding study of TNF complexed with MAb 32 (—◆—), control antibody, and MAb 47 (—▪—) on the melanoma cell line MM418E.
Figure 6 shows the effect of MAb 32 (▪) control MAb and MAb 47 (*) on TNF-mediated tumor regression in vivo.
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