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Creative Biolabs
Product

NeuroMab™ Anti-VAChT vesicular acetylcholine transporter BBB Shuttle Antibody, Clone N6/38

[CAT#: NRZP-0423-ZP453]

Species Reactivity:
Human; Mouse; Rat
Applications:
WB; IHC; ICC

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Product Overview

Description

The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-VAChT BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.

Immunogen

Synthetic peptide amino acids 521-532 (CEDDYNYYYTRS) of human VAChT (accession number NP_003046)
Rat: 83% identity (10/12 amino acids identical)
Mouse=83% identity (10/12 amino acids identical)

Construction

We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

N6/38

Applications

WB; IHC; ICC

Research Areas

Transporters

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

VAChT

Official Name

SLC18A3

Full Name

VAChT

Alternative Names

SLC18A3; VACHT; solute carrier family 18 member A3; CMS21

Uniprot ID

NP_003046
Product Pictures
IHC

Fig. 1 Adult rat brain immunohistochemistry.

Publications

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For Research Use Only. Not For Clinical Use.
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