NeuroMab™ EGFR BBB Shuttle(NRZP-1022-ZP4119)

Product Overview

Description

Brain uptake of therapeutic proteins is severely limited by their size. Creative Biolabs has developed a BBB shuttle platform that actively transports these large biomolecules across the BBB via receptor-mediated transcytosis (RMT). The engineered BBB shuttle protiens is believed to significantly increase the uptake of therapeutic molecules in the brain.

Species Reactivity

Human

Clonality

Monoclonal

Applications

In Vitro

Relevant Diseases

Alzheimer's Disease; Pain; Multiple Sclerosis

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

EGFR

Official Name

EGFR

Full Name

Epidermal Growth Factor Receptor

Alternative Names

Epidermal Growth Factor Receptor; Receptor Tyrosine-Protein Kinase ErbB-1; Erb-B2 Receptor Tyrosine Kinase 1; Proto-Oncogene C-ErbB-1; EC 2.7.10.1; ERBB1; ERBB; HER1; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian);

Publications