EGFR Therapeutic Aptamer (CL-4RNV616)

[CAT#: NV-2106-P79]

Target:: EGFR

Product Type:: Aptamers

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Product Overview

Description

Aptamer Role: Antagonist
SELEX Method: Cell-based SELEX
KD (nmol/L): 18.24
Composition: 2'-O-methyl RNA and DNA
Therapeutic Application: Reduce cell proliferation

Properties

Research Use Only

This product is for research use only.

Target Details

Target

EGFR

Official Name

EGFR

Full Name

Epidermal Growth Factor Receptor

Alternative Names

Epidermal Growth Factor Receptor; Receptor Tyrosine-Protein Kinase ErbB-1; Erb-B2 Receptor Tyrosine Kinase 1; Proto-Oncogene C-ErbB-1; EC 2.7.10.1; ERBB1; ERBB; HER1; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian);

Gene ID

1956(Human); 13649(Mouse); 24329(Rat)

Uniprot ID

P00533(Human); Q01279(Mouse)

References

Wang, T., Philippovich, S., Mao, J., & Veedu, R. N. (2019). Efficient epidermal growth factor receptor targeting oligonucleotide as a potential molecule for targeted cancer therapy. International journal of molecular sciences, 20(19), 4700.
under Open Access license CC BY 4.0, without modification.

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