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Creative Biolabs
Product

Mouse Anti-MARCKS Monoclonal Antibody (CBP6636)

[CAT#: NAB2007FY1497]

Mouse Monoclonal to MARCKS

Host Species:
Mouse
Species Reactivity:
Human; Monkey
Applications:
WB; IF; IHC

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Product Overview

Description

The myristoylated alanine-rich C kinase substrate, therefore MARCKS, was originally discovered as the main substrate of protein kinase C in the brain and other tissues (1). The protein sequence is indeed abnormally rich in alanine, and the human sequence contains 30.7% alanine. It is also rich in glutamic acid (16.0%), proline (10.5%) and glycine (10.2%). This sequence has almost no hydrophobic amino acids, with a calculated molecular weight of 31.4kDa and a PI of 4.46. These unusual features are responsible for the low mobility of SDS-PAGE, which has an apparent molecular weight of 80kDa.

Immunogen

Full-length human MARCKS expressed and purified in E. coli.

Species Reactivity

Human; Monkey

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6636

Applications

WB; IF; IHC

Application Notes

WB: 1:2000
IF/ICC and IHC: 1:2000
Product Properties

Form

Liquid

Formulation

50% PBS, 50% glycerol

Preservatives

5mM NaN3

Concentration

1 mg/ml

Shipping

Gel Pack

Storage

Store at 4°C for short term, for longer term at -20°C

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

MARCKS

Official Name

MARCKS

Full Name

Myristoylated alanine rich protein kinase C substrate

Alternative Names

MARCKS; 80K-L; MACS; PKCSL; PRKCSL; myristoylated alanine rich protein kinase C substrate

Gene ID

4082(Human)

Uniprot ID

P29966(Human)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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