NeuroMab™ Anti-BKBeta2 potassium channel subunit, Clone N53/32 (CBP8146)

Product Overview

Immunogen

Fusion protein amino acids 1-41 (MFIWTSGRTSSSYRQDEKRNIYQKIRDHDLLDKRKTVTALK, cytoplasmic N-terminus) and 218-235 (KLTQYLSLLCERIQRINR, cytoplasmic C-terminus) of mouse BKBeta2 (also known as BK channel subunit beta-2, Calcium-activated potassium channel subunit beta-2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, K(VCA)beta-2, Maxi K channel subunit beta-2, Slobeta-2 and Kcnmb2, accession number Q9CZM9)
Human: 97% and 100% identity (40/41 and 18/18 amino acids identical, respectively)
Rat: 97% and 100% identity (40/41 and 18/18 amino acids identical, respectively)
<50% identity with other BKBeta subunits

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

CBP8146

Applications

WB; IHC; ICC

Application Notes

No cross-reactivity against BKBeta1, BKBeta3 or BKBeta4

Research Areas

K+ channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

KCNMB2

Official Name

KCNMB2

Full Name

BKbeta2 K+ channel

Alternative Names

KCNMB2; potassium calcium-activated channel subfamily M regulatory beta subunit 2

Uniprot ID

Q9CZM9

Product Pictures

Fig. 1 Immunoblot against extracts of COS cells transiently transfected with GFP-tagged BKBeta2 or untagged Kv2.1 plasmid and probed with N53/32 (left) or K89/41 (right) TC supe.

Fig. 2 Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with N53/32 (left) or N52A/42 (right) TC supe.

Publications