NeuroMab™ Anti-Cav1.2, Clone N263/31 (CBP8161)

Product Overview

Immunogen

Fusion protein amino acids 808-874 (cytoplasmic loop between repeat II and III) of rat Cav1.2 (also known as Voltage-dependent L-type calcium channel subunit alpha-1C, CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1, Brain class C and MELC-CC, accession number P22002)
Mouse: 100% identity (67/67 amino acids identical)
Human: 86% identity (58/67 amino acids identical)
<<50% identity with other Cav1 channels

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

CBP8161

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with Cav1.3

Research Areas

Ca2+ channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

CACNA1C

Official Name

CACNA1C

Full Name

Cav1.2 Ca2+ channel

Alternative Names

Calcium Voltage-Gated Channel Subunit Alpha1 C; Calcium Channel; L Type; Alpha-1 Polypeptide; Isoform 1; Cardiac Muscle; Calcium Channel; Voltage-Dependent; L Type; Alpha 1C Subunit; CACNL1A1; CCHL1A1; CACH2; CACN2; Voltage-Gated L-Type Calcium Channel Cav1.2 Alpha 1 Subunit; Splice Variant 10*; Calcium Channel; Cardic Dihydropyridine-Sensitive; Alpha-1 Subunit;

Uniprot ID

P22002

Product Pictures

Fig. 1 Tissue and transfected cell immunoblot: extracts of rat brain membrane (RBM) and COS cells transiently transfected with untagged Cav1.2, Cav1.3 or Kv2.1 plasmids and probed with N263/31 (left) and L57/46 (right) TC supe.

Publications