NeuroMab™ Anti-GABA-A-R-Alpha5, Clone N415/24 (CBP8213)

[CAT#: NRP-0422-P112]

Species Reactivity:: Human; Mouse; Rat

Applications:: WB; IHC; ICC

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Product Overview

Immunogen

Fusion protein amino acids 368-419 (last cytoplasmic domain before extracellular C-terminus) of human GABA-A-R-Alpha5 (also known as Gamma-aminobutyric acid receptor subunit alpha5, GABA(A) receptor subunit alpha-5 and Gabra5, accession number P31644)
Mouse: 78% identity (41/52 amino acids identical)
Rat: 73% identity (39/53 amino acids identical)
<50% identity with GABA-A-R-Alpha2 and other GABA-A receptors

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8213

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with GABA-A-R-Alpha2 (or other GABAA receptors based on KO validation data)

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

GABA A Receptor Alpha 5

Official Name

GABRA5

Full Name

GABA(A)R, Alpha5

Alternative Names

GABRA5; gamma-aminobutyric acid type A receptor alpha5 subunit; EIEE79; gamma-aminobutyric acid type A receptor subunit alpha5

Uniprot ID

P31644

Product Pictures

Fig. 1 Immunoblot against crude low-speed pellet fractions from adult rat brain (RBLSP) and wild-type (WT) and GABA-A-RAlpha5 knockout (KO) mouse brains probed with N415/24 (left) and N52A/42 (right) TC supe.

Publications