NeuroMab™ Anti-MOG BBB Shuttle Antibody, Clone L94/54
[CAT#: NRZP-0423-ZP274]
- Species Reactivity:
- Rat
- Applications:
- WB; IHC; ICC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-MOG BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-125 (third intracellular loop) of rat MOG (also known as Myelinoligodendrocyte glycoprotein, accession number Q6MFX9)
Mouse: 88% identity (111/126 amino acids identical)
Human: 90% identity (90/100 amino acids identical)
Mouse: 88% identity (111/126 amino acids identical)
Human: 90% identity (90/100 amino acids identical)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
L94/54
Applications
WB; IHC; ICC
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
MOG
Official Name
MOG
Full Name
MOG
Alternative Names
MOG
Uniprot ID
Q6MFX9
Product Pictures
IHC
Fig. 1 Adult rat hippocampus immunohistochemistry (with antigen retrieval via Na citrate pretreatment).
IHC
Fig. 2 Adult rat cerebellum immunohistochemistry (with antigen retrieval via Na citrate pretreatment).
IHC
Fig. 3 Adult rat whole brain immunohistochemistry (with antigen retrieval via Na citrate pretreatment)
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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