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Creative Biolabs

NeuroMab™ Anti-Nogo Antibody(NRP-0422-P1654)

[CAT#: NRP-0422-P1654]

Functional antibody against Human NogoR

Host Species:
Mouse
Species Reactivity:
Human
Applications:
ELISA; In Vitro; In Vivo; Neut

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Product Overview

Description

The antibody specifically binds to the Nogo receptor (NogoR), has the ability to compete MAG binding to soluble NogoRS; and inhibit binding of NOGO66 ligand to rHuNOGOSR. The antibody has uses, for example, in the treatment of spinal cord injury, brain trauma, paralysis, degenerative nervous system diseases, and stroke.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

ELISA; In Vitro; In Vivo; Neut

Relevant Diseases

Alzheimer's Disease; Parkinson's Disease; Multiple Sclerosis; Amyotrophic Lateral Sclerosis
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

Nogo

Official Name

RTN4R

Full Name

Reticulon 4 receptor

Alternative Names

RTN4R; NGR; NOGOR; Reticulon 4 receptor

Gene ID

65078(Human); 65079(Mouse)

Uniprot ID

Q9BZR6(Human); Q99PI8(Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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