NeuroMab™ Anti-Synaptotagmin-7 BBB Shuttle Antibody, Clone N275/14
[CAT#: NRZP-0423-ZP411]
- Species Reactivity:
- Mouse; Rat
- Applications:
- WB; IHC; ICC
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-Synaptotagmin 7 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 150-239 (cytoplasmic C2A domain) of mouse Synaptotagmin-7 (also known as Syt7, Synaptotagmin VII and SytVII, accession number Q9R0N7)
Rat: 98% identity (89/90 amino acids identical)
Human: 97% identity (88/90 amino acids identical)
>50% identity with Synaptotagmin-6 (and other Synaptotagmins)
Rat: 98% identity (89/90 amino acids identical)
Human: 97% identity (88/90 amino acids identical)
>50% identity with Synaptotagmin-6 (and other Synaptotagmins)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Mouse; Rat
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
N275/14
Applications
WB; IHC; ICC
Application Notes
Does not cross-react with Synaptotagmin-6 (or other Synaptotagmins)
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
Synaptotagmin 7
Official Name
SYT7
Full Name
Synaptotagmin-7
Alternative Names
SYT7; IPCA-7; IPCA7; PCANAP7; SYT-VII; SYTVII; synaptotagmin 7
Uniprot ID
Q9R0N7
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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