NeuroMab™ Mouse Anti-IL-1 Beta Monoclonal Antibody (CBP2533)
[CAT#: NAB2007FY889]
Mouse Monoclonal [1A7] to IL-1 Beta
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Mouse anti-interleukin-1 beta. The protein encoded by IL1B is a member of the interleukin-1 cytokine family. This cytokine is produced by activated macrophages in the form of original protein, which is proteolyzed by caspase 1 (CASP1/ICE) into its active form. This cytokine is an important mediator of inflammatory response and participates in a variety of cell activities, including cell proliferation, differentiation and apoptosis. It was found that this cytokine induces cyclooxygenase 2 (PTGS2/COX2) in the central nervous system (CNS) to contribute to inflammatory pain hypersensitivity. IL1B and 8 other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (provided by RefSeq, July 2008).
Immunogen
HEK293-derived full-length recombinant IL-1 beta.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP2533
Applications
WB
Application Notes
WB: 1/1000
Relevant Diseases
Amyotrophic Lateral Sclerosis; Frontotemporal Dementia
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1853
Product Properties
Form
Liquid
Formulation
PBS, 0.09% Sodium Azide, 1% Bovine Serum Albumin
<50% Glycerol
<50% Glycerol
Preservatives
YES
Concentration
1 mg/ml
Purification
Protein G
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
Neural Antibodies
Neural Genes
For Research Use Only. Not For Clinical Use.
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