Mouse Anti-MAP2A/B Monoclonal Antibody (CBP6672)

Description

Microtubules are protein rods with a diameter of 25 nanometers found in most eukaryotic cells and are related to a family of proteins called microtubule-associated proteins (MAP). MAPs play a crucial role in the regulation of microtubule dynamics and interactions in vivo. MAP2 was originally named one of the higher molecular weight MAPs, and its SDS-PAGE molecular weight was about 280kDa (1-3). There is a mammalian MAP2 gene, which can produce two high-molecular-weight proteins of about 280kDa, called MAP2A and MAP2B, and a variety of low-molecular-weight forms, usually called MAP2C and MAP2D, which are in the 60-70kDa SDS-PAGE gel Run on. Lower molecular weight forms are found in neurons in the early stages of development, but as animals mature, they are replaced by higher molecular weight forms (2). The MAP2A and MAP2B forms include a protein sequence that forms filamentous protrusions from the side of brain microtubules, so it is called the projection domain.

Immunogen

Full-length MAP2A/B purified from bovine spinal cord

Species Reactivity

Human; Rat; Mouse; Cow

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6672

Applications

WB; IF; IHC

Application Notes

WB: 1:10000
IF/ICC and IHC: 1:1000

Form

Liquid

Formulation

50% PBS, 50% glycerol

Preservatives

5mM NaN3

Concentration

1 mg/ml

Shipping

Gel Pack

Storage

Stable at 4°C for one year, for longer term store at -20°C

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only

Target

MAP2

Official Name

MAP2

Full Name

Microtubule Associated Protein 2

Alternative Names

SNCA; Microtubule Associated Protein 2; MAP2

Gene ID

4133(Human); 17756(Mouse); 25595(Rat)