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Creative Biolabs
Product

NeuroMab™ Anti-GFAP, Clone N206A/8 (CBP8237)

[CAT#: NRP-0422-P136]

Species Reactivity:
Human; Mouse; Rat
Applications:
WB; IHC; ICC

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Product Overview

Immunogen

Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP (also known as Glial fibrillary acidic protein, accession number P14136)
Rat: 100% identity (12/12 amino acids identical)
Mouse: 100% identity (12/12 amino acids identical)
>50% identity with other proteins (Vimentin, Desmin, Tumor protein p73 and Peripherin)

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8237

Applications

WB; IHC; ICC

Application Notes

Cross-reacts with GFAP-R416W and other GFAP mutant proteins;Does not cross-react with other proteins (based on KO validation results)

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

GFAP

Official Name

GFAP

Full Name

GFAP

Alternative Names

Glial Fibrillary Acidic Protein; Intermediate Filament Protein; ALXDRD;

Uniprot ID

P14136
Product Pictures
IB

Fig. 1 Immunoblot versus low speed pellet samples from rat brain (RBLSP) and wild-type (WT), GFAP knockout (KO) and GFAP-R416W mutant knockin (KI) mice and probed with N206A/8 (left), mutant control(middle) and N52A/42 (right).

IF

Fig. 2 Adult WT and KO mouse hippocampus immunofluorescence with N206A/8 (green) and KC rabbit antiKv2.1 (red).

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