NeuroMab™ Anti-Nav1.5 sodium channel, Clone N397/19 (CBP8382)

[CAT#: NRP-0422-P281]

Species Reactivity:: Human; Mouse; Rat

Applications:: WB; IHC; ICC

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Product Overview

Immunogen

Fusion protein amino acids 424-658 (cytoplasmic loop between repeats I and II) of human Nav1.5 (also known as Voltage-gated sodium channel subunit alpha Nav1.5, Sodium channel protein type 5 or V subunit alpha, Sodium channel protein cardiac muscle subunit alpha, SCN5A and HH1, accession number Q14524)
Mouse: 88% identity (209/235 amino acids identical)
Rat: 87% identity (206/235 amino acids identical)
<40% identity with Nav1.1 and other Nav1 channels

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8382

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with Nav1.4

Research Areas

Na+ channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

SCN5A

Official Name

SCN5A

Full Name

Nav1.5 Na+ channel

Alternative Names

SCN5A; CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1; sodium voltage-gated channel alpha subunit 5

Uniprot ID

Q14524

Product Pictures

Fig. 1 Immunoblot against extracts of COS cells transiently transfected with untagged Nav1.4, Nav1.5 or Kv2.1 plasmid probed with N397/19 (left) or K58/35 (right) TC supe.