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Creative Biolabs
Product

Anti-LINGO1/LRRN6A/LERN1 Antibody (CBP4534)

[CAT#: NAB-PA-P005]

Host Species:
Human
Species Reactivity:
Human
Applications:
In Vitro

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Product Overview

Description

Opicinumab is a human monoclonal antibody that targets LINGO-1, a protein known to suppress remyelination and regrowth of transected axons. By blocking LINGO-1, opicinumab has been shown to promote remyelination in vivo.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Isotype

IgG1-kappa

Clone Number

Opicinumab Biosimilar

Applications

In Vitro

Relevant Diseases

Multiple Sclerosis
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regualr Endotoxin < 5EU/mg
Low endotoxin < 1EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

CGRP

Official Name

CGRP

Alternative Names

CALCA; CALC1; CGRP; CGRP-I; CGRP1; CT; KC; PCT; calcitonin related polypeptide alpha; CGRP-alpha;CALCB; BIIB-033
Publications

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For Research Use Only. Not For Clinical Use.
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