NeuroMab™ Anti-PSD-95 MAGUK scaffold protein, Clone K28/74 (CBP8457)

Product Overview

Immunogen

Fusion protein amino acids 77-299 (PDZ domains 1 and 2) of human PSD-95 (also known as Postsynaptic density protein 95, Disks large homolog 4, Synapseassociated protein 90, DLG4, Dlgh4 and SAP-90, accession number P78352)
Rat: 100% identity (223/223 amino acids identical)
Mouse: 99% identity (221/223 amino acids identical)
65-80% identity with DLG1/SAP97,
DLG2/Chapsyn-110 and DLG3/SAP102

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8457

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with DLG1/SAP97, DLG2/Chapsyn-110 or DLG3/SAP102

Research Areas

Scaffolds

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

PSD 95

Official Name

DLG4

Full Name

PSD-95

Alternative Names

DLG4; PSD95; SAP-90; SAP90; Dlgh4; PSD-95; SAP90A; discs large homolog 4; discs large MAGUK scaffold protein 4; MRD62

Uniprot ID

P78352

Product Pictures

Fig. 1 Immunoblot against adult rat brain membranes (RBM) and adult mouse hippocampal membranes (MHM) from PSD95 or PSD-93 knockout (KO) mice probed with K28/74 (left) or K28/86 (right) TC supe.

Fig. 2 Immunofluorescence of human frontal cortex with K28/74 (green), rabbit Synapsin-1 (red) and DAPI (blue). Twelve images from 100 nm sections (left) were volume-reconstructed via array tomography (31.5 x 34x 1.2m, right).