NeuroMab™ Anti-CD34 BBB Shuttle Antibody(NRZP-1022-ZP3715)
[CAT#: NRZP-1022-ZP3715]
- Host Species:
- Humanized
- Species Reactivity:
- Human
- Applications:
- ELISA; FC; Inhib
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Humanized
Isotype
IgG
Applications
ELISA; FC; Inhib
Relevant Diseases
Amyotrophic Lateral Sclerosis
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
CD34
Official Name
CD34
Full Name
CD34 Molecule
Alternative Names
CD34 Molecule; CD34 Antigen;
Product Pictures
SDS-PAGE
Figure 1 shows mMy10 IgG and hMy10 IgG purified in SDS-PAGE analysis according to one embodiment.
ELISA
Figure 2 shows the binding affinity of two-fold dilutions of mMy10 IgG and hMy10 IgG to CD34+ KG1a cells according to one embodiment.
ELISA
Figure 3 shows the binding affinity of QBen10 IgG, mMy10 IgG and hMy10 IgG to CD34+KG1a cells according to one embodiment.
FCM
Figure 4 shows the isolation of CD34+ cells using immunomagnetic beads carrying hMy10 IgG according to one embodiment.
ELISA
Figure 5 shows the results of a study on CD34+ cell capture using hMy10 IgG according to one embodiment.
FuncS
Figure 6 shows the results of capturing CD34+ cells from the bloodstream in a dynamic model by using the hMy10 IgG antibody.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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